More vitamin D may mean faster recovery from muscle injury

More vitamin D may mean faster recovery from muscle injury

Increased blood levels of vitamin D may increase the rate of muscle recovery after intensive exercise, says a new study from Utah-based scientists.

“Muscle weakness hinders millions of people worldwide every year and is mediated by a variety of conditions, including aging, disease, inactivity, limb immobilization, repetitive use, and intense or unaccustomed exercise,” explained the researchers in the journal Nutrients.

“In the present investigation, we reveal that muscular weakness after an intense exercise bout is abrogated with increasing serum 25(OH)D concentration prior to exercise. However, this was apparent immediately and several days (2-day and 3-day), but not 1-day, after intense exercise.”

The data indicate that maintaining vitamin D levels – as measured by 25(OH)D levels – could help diminish muscular weakness after intense exercise.

The study was performed by researchers from The Orthopedic Specialty Hospital in Murray, Utah, ARUP Laboratories, Salt Lake City, the University of Utah, Salt Lake City, USANA Health Sciences, the Intermountain Medical Center in Murray, and the LDS Hospital in Salt Lake City.

The sunshine vitamin

Vitamin D refers to two biologically inactive precursors - D3, also known as cholecalciferol, and D2, also known as ergocalciferol.

Both D3 and D2 precursors are transformed in the liver and kidneys into 25- hydroxyvitamin D (25(OH)D), the non-active 'storage' form, and 1,25-dihydroxyvitamin D (1,25(OH)2D), the biologically active form that is tightly controlled by the body.

Vitamin D is unique in that it can be both ingested and synthesized by the body with sun exposure. It is then converted by both the liver and kidneys to a form that the body can use.

An individuals' vitamin D status is determined by measuring the level of 25-hydroxyvitamin D in the blood.

Vitamin D deficiency, which is defined as a status of less than 20 nanograms per milliliter (ng/mL) of 25-hydroxyvitamin D, can cause a number of health issues, including rickets and other musculoskeletal diseases.

Recently, however, data suggests that vitamin D deficiency (<20 ng/mL) and vitamin D insufficiency (between 21-29 ng/mL) may be linked to cancer, autoimmune diseases, infectious diseases, type 2 diabetes and cardiovascular disease.

Study details

Led by Tyler Barker, the researchers recruited 14 recreationally active adults to participate in their study.

One leg was used for the muscle performance experiment, while the other acted as control, and compared to blood levels of vitamin D, and a series of other blood chemicals.

Results showed that, as expected, muscular weakness was observed in the exercise leg, compared with the control leg after the exercise protocol. Blood levels of vitamin D inversely predicted muscular weakness, said the researchers both immediately and several days after exercise.

“The novel finding of the present investigation was the inverse association between pre-exercise serum 25(OH)D and both immediate and persistent muscular weakness after intense exercise,” wrote the researchers.

“Given the feasibility of increasing 25(OH)D concentrations in the blood, future research investigating the influence of diverse vitamin D interventions on the alleviation of muscular weakness after muscular insult are encouraged in humans.”

Source: Nutrients
2013, Volume 5, Number 4, Page 1253-1275, doi:10.3390/nu5041253
“Higher Serum 25-Hydroxyvitamin D Concentrations Associate with a Faster Recovery of Skeletal Muscle Strength after Muscular Injury”
Authors: T. Barker , V.T. Henriksen , T.B. Martins, et al. 

Related News

Vitamin D may reduce risk of uterine fibroid: Study

Vitamin D may reduce risk of uterine fibroid: Study

Vitamin D may ease exercise-related muscle damage: Animal data

Vitamin D may ease exercise-related muscle damage: Animal data

Low vitamin D levels may speed up bone aging

Low vitamin D levels may speed up bone aging

Supplementation with vitamin D could help to reverse deficiencies in the sunshine vitamin that are impacting ICU infection rates and increasing the length of hospital stays, according to the researchers.

Medical Nutrition: Vitamin D supplements backed for ICU infections

Strong China sales push Usana to record results

Strong China sales push Usana to record results

Review questions vitamin D for reducing chronic disease risk

Review questions vitamin D for reducing chronic disease risk

Mushrooms provide as much vitamin D as supplements, researchers find

Mushrooms provide as much vitamin D as supplements, researchers find

Vitamin D supplements may yield immune benefits in healthy people

Vitamin D supplements may yield immune benefits in healthy people: Study

Do vitamin D levels influence genes for immune health?

Do vitamin D levels influence genes for immune health?

Vitamin D in the US: ‘Those with greatest need of dietary sources of vitamin D have the lowest intakes’

Vitamin D in the US: ‘Those with greatest need of dietary sources of vitamin D have the lowest intakes’

Submit a comment

Your comment has been saved

Post a comment

Please note that any information that you supply is protected by our Privacy and Cookie Policy. Access to all documents and request for further information are available to all users at no costs, In order to provide you with this free service, William Reed Business Media SAS does share your information with companies that have content on this site. When you access a document or request further information from this site, your information maybe shared with the owners of that document or information.