Certain probiotics could help women lose weight, study finds

Certain probiotics could help women lose weight, study finds

Supplementation with certain probiotics containing Lactobacillus rhamnosus may help women lose weight and keep it off, according to new research.

The study, published in the British Journal of Nutrition, aimed to determine whether the consumption of probiotics could help reset the balance of the intestinal microbiota in favour of bacteria that promote a healthy weight - finding that women who consumed probiotics of the species Lactobacillus rhamnosus in conjunction with a weight loss diet lost more weight than those who consumed a placebo and the weight loss diet. However, the team noted that this finding was only true in women, adding that there was no significant difference between placebo and the probiotic for weight loss in men.

Led by Professor Angelo Tremblay from the Université Laval, the team noted that previous studies have demonstrated that the intestinal flora of obese individuals differs from that of thin people, and that this difference may be due to the fact that a diet high in fat and low in fibre promotes certain bacteria at the expense of others.

"We don't know why the probiotics didn't have any effect on men. It may be a question of dosage, or the study period may have been too short," said Tremblay.

Study details

Tremblay and his colleagues recruited 125 overweight men and women who underwent a 12-week weight-loss diet followed by a 12-week period aimed at maintaining body weight.

Throughout the entire study half of the participants were given 2 pills daily containing probiotics from the Lactobacillus rhamnosus family, while the other half received a placebo.

After the 12-week diet period, researchers observed an average weight loss of 4.4 kg in women in the probiotic group and 2.6 kg in the placebo group. However, no differences in weight loss were observed among males in the two groups.

Upon completion of the 12-week maintenance period, the weight of the women in the placebo group had remained stable but the probiotic group had continued to lose weight, to a total of 5.2 kg per person, said Tremblay and his colleagues.

Indeed, by the end of the 24 week study women consuming probiotics lost twice as much weight as those receiving the placebo. The team also noted a drop in the appetite-regulating hormone leptin in this group, as well as a lower overall concentration of the intestinal bacteria related to obesity.

While the current study focused on only one strain of Lactobacillus rhamnosus, Tremblay noted that other probiotics found in dairy products could have a similar effect. He stressed, however, that the benefits of these bacteria are more likely to be observed in a favourable nutritional context that promotes low fat and adequate fibre intake.

Source: British Journal of Nutrition
Published online ahead of print, doi: 10.1017/S0007114513003875
"Effect of Lactobacillus rhamnosus CGMCC1.3724 supplementation on weight loss and maintenance in obese men and women"
Authors: Marina Sanchez, Christian Darimont et al

Related News

Microbiota may communicate with human gut cells through enzyme signalling

Microbiota may communicate with human gut cells through enzyme signalling

People living at more northern lattitudes have a different relative abundance ot key obesity-linked microbes, according to the new data.

Gut geography: Are obesity-linked gut bacteria more prevalent in northern areas?

Dietary fibres could help battle obesity by driving changes in the ratio of bacterial species in our gut microbiota.

Gut bacteria ‘shift’ from fibre could aid weight loss

On-pack probiotic claims possible with medical women's health products, says Danish supplier Bifodan

Is the future of women’s health probiotics medical?

An imbalance in microbial populations in the gut has been linked to obesity, and may promote intestinal inflammation-induced metabolic disorders, including insulin resistance and diabetes.

Probiotics may benefit energy metabolism in obese people: Human data

Probiotic cheese + low calorie diet shows weight and heart health benefits for obese

Probiotic cheese + low calorie diet shows weight and heart health benefits for obese

Gut bacteria are closely linked to immune functions

Gut bacteria are closely linked to immune functions, review suggests

Gut health and obesity: Human gut bacteria can alter mouse metabolism, depending on diet, says new study

Gut health and obesity: Human gut bacteria can alter mouse metabolism, depending on diet, says new study

Waste products from mushroom harvesting could be used to help the survival of probiotics in foods, suggest the researchers.

Prebiotic potential: Mushroom ‘waste’ could enhance probiotic survival

"Our results indicate that probiotics are of potential therapeutic utility to counter obesity and diabetes" - Dr Hariom Yadav, et al.

Probiotics may ‘counter obesity and diabetes’: NIH study

Related Products

See more related products

Comments (4)

Rose - 22 Jun 2016 | 10:39


Will ProBio5 help clear up a rash (poison ivy perhaps) if I take it along with Prednisone and also knee joint pain?

22-Jun-2016 at 22:39 GMT

Stella Metsovas B.S. - 19 Feb 2014 | 11:05

Bacteria in the Gut

We're just beginning tap into the information our gut microbiome holds. Including naturally fermented food products--addition to supplementation-- is most favorable for balance gut microbes. Yours in Health, Stella Metsovas B.S. www.stellametsovas.com

19-Feb-2014 at 23:05 GMT

Submit a comment

Your comment has been saved

Post a comment

Please note that any information that you supply is protected by our Privacy and Cookie Policy. Access to all documents and request for further information are available to all users at no costs, In order to provide you with this free service, William Reed Business Media SAS does share your information with companies that have content on this site. When you access a document or request further information from this site, your information maybe shared with the owners of that document or information.